A team of researchers from the Wang Yangming Laboratory at Peking University’s College of Future Technology has recently identified a DddA homolog from Simiaoa sunii (Ddd_Ss) that can efficiently deaminate cytosine in DC context in double-stranded DNA (dsDNA). Their findings were published on February 16, 2023 in Nature Communications, titled “DddA homolog search and engineering expand sequence compatibility of mitochondrial base editing.”
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Source: Phys.org