Germline stem and progenitor cells (GSPCs), including primordial germ cells (PGCs) and germline stem cells (GSCs), generate various states of germ stem cells and then differentiate into specialized cells, while self-renewing to generate more stem cells. The formation, maintenance and differentiation of GSPCs are essential for the animal reproduction process and are regulated by a multitude of mechanisms.
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Source: Phys.org