Transcription factor IIH, or TFIIH, pronounced “TF two H,” is a veritable workhorse among the protein complexes that control human cell activity. It plays critical roles both in transcription—the highly regulated enzymatic synthesis of RNA from a DNA template—and in the repair of damaged DNA. But how can one protein assembly participate in two such vastly different and extremely important genomic tasks?
Click here for original story, DNA-repair protein complex is a shapeshifter, reconfiguring itself to meet the demands of each task
Source: Phys.org