Organosulfur(VI) fluoride compounds display excellent chemical stability, and yet can efficiently realize diverse linkages via the activation of specific conditions. Based on its unique nature, Sharpless, Dong and coworkers introduced SuFEx as a new generation of click reaction in 2014. Since then, SuFEx has become an active research area, frequently occurring in chemical biology, drug discovery, and material chemistry.
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Source: Phys.org