Why S-linked glycosylation cannot adequately mimic the role of natural O-glycosylation

Protein glycosylation is one of the most important post-translational modifications that can be exploited to improve various aspects of therapeutic proteins and industrial enzymes. Different types of glycosylation have a variety of effects on protein properties and functions, and a better understanding of the underlying mechanisms can provide valuable guidance for rational glycoengineering of proteins.


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Source: Phys.org