Reassembly of parallel trimolecular G-quadruplex via novel Hoogsteen strand displacement reaction

Using solution-state Nuclear Magnetic Resonance (NMR) technology, a group of scientists led by Prof. Zhang Na from Hefei Institutes of Physical Science (HFIPS) of Chinese Academy of Sciences (CAS) recently discovered a novel reassembly process for G-quadruplexes (GQs) through a new type of reaction called Hoogsteen pairing-based Strand Displacement Reaction (Hoogsteen SDR).


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Source: Phys.org