One treatment for deep vein thrombosis (DVT) is a procedure called catheter-directed thrombolysis (CDT). CDT has become more commonly used in the US since research showed it reduced the incidence of post-thrombotic syndrome. A team sought to identify and describe sex-based differences in utilization and safety outcomes of CDT for treatment of DVT in the U.S. The team found sex-based differences in both utilization and safety outcomes.