Cancer exports molecular ‘saboteurs’ to remotely disarm immune system

Immunotherapy drugs known as checkpoint inhibitors have revolutionized cancer treatment: many patients with malignancies that until…

Insulin receptor and gene expression

Insulin triggers genome-wide changes in gene expression via an unexpected mechanism. The insulin receptor is transported…

Research improves understanding of new form of cell-cell communication

Scientists have improved their understanding of a new form of cell-cell communication that is based on…

Blocking epigenetic Swiss army knife may be a new strategy for treating colorectal cancer

A new study shows that blocking specific regions of a protein called UHRF1 switches on hundreds…

Federal subsidies for US commercial fisheries should be rejected, analysis concludes

A pending rule change proposed by the US National Marine Fisheries Service would allow the use…

Poverty leaves a mark on our genes

In this study, researchers found evidence that poverty can become embedded across wide swaths of the…

Using a promiscuous inhibitor to uncover cancer drug targets

Scientists have developed a method that exploits the multitargeted nature of a chemical inhibitor to pinpoint…

To keep the creative juices flowing, employees should be receptive to criticism

Though most firms today embrace a culture of criticism, when supervisors and peers dispense negative feedback…

Severe psychological distress and daily cannabis use: Implications for mental health?

Daily cannabis use increased significantly from 2008 to 2016 among those with and without past-month serious…

Parkinson’s clues seen in tiny fish could aid quest for treatments

Parkinson's patients could be helped by fresh insights gained from studies of tiny tropical fish. Research…