Researchers have demonstrated in animal models that a protein called NLRP2 plays an important role in early embryogenesis, the process of cell division in fertilized eggs that occurs before they implant into the lining of the uterus. In addition, the protein was shown to become more important with increasing maternal age, as blocking NLRP2 in eggs prevented them from developing in blastocysts. As a similar protein exists in humans, these insights may lead to greater understanding of reproductive disorders and novel paths to treatment, report investigators.