Much remains to be understood about how proteins in the human body works in unison; however a newly developed resource is giving scientists a more complete picture of how the proteome makes us uniquely human. MissingProteinPedia, a database developed by a collaborative research group lead by scientists at Macquarie University, could not only help researchers learn more about the location and use – termed ‘expression’ – of specific proteins in the body but also how they interact to make us human. It will also help to pin down those proteins which are still ‘in the shadows’, with implications for several diseases.