OsteoOmics: The crew changed BioCell media in BioCell Habitat 4. The media in all four of the habitats are changed in this second of four weeks of OsteoOmics operations. Crewmembers experience bone loss in orbit, stemming from the lack of gravity acting on their bones. OsteoOmics investigates the molecular mechanisms that dictate this bone loss by examining osteoblasts, which form bone, and osteoclasts, which dissolve bone. Improved understanding of these mechanisms could lead to more effective countermeasures to prevent bone loss during space missions and in a wide range of disorders on Earth. This may lead to better preventative care or therapeutic treatments for people suffering bone loss as a result of bone diseases like osteopenia and osteoporosis, or for patients on prolonged bed rest. Fine Motor Skills (FMS): The crew completed a series of interactive tasks during a FMS session today. The FMS investigation studies how the fine motor skills are effected by long-term microgravity exposure, different phases of microgravity adaptation, and sensorimotor recovery after returning to Earth gravity. The goal of the investigation is to determine how fine motor performance in microgravity trends/varies over the duration of a six-month and year-long space mission; how fine motor performance on orbit compare with that of a closely matched participant on Earth; and how performance trends/varies before and after gravitational transitions, including periods of early flight adaptation and very early/near immediate post-flight periods. Extravehicular Activity (EVA) Preparations: In preparation for tomorrow’s planned EXPRESS Pallet Controller Assembly (ExPCA) EVA, the crew verified tools are configured properly and that batteries are installed in Pistol Grip Tools and cameras. They also performed a final procedures review and conference with ground teams followed by final Equipment Lock preparation. Egress is scheduled tomorrow at 7:10AM CDT. Today’s Planned Activities All activities were completed unless otherwise noted. MARES battery discharge process initiation Personal Data Prep for Return ISS Food Intake Tracker – Screenshot Captures IMS Delta file prep URAGAN. Observation and photography EKON-M. Observations and photography OsteoOmics MELFI Removal Health Maintenance System (HMS) Periodic Health Status (PHS) Pre EVA Examination Filling (separation) of ЕДВ (КОВ) for Elektron or ЕДВ-СВ Fine Motor Skills Experiment Test – Subject MARES knee configuration deinstallation Health Maintenance System (HMS) Pre-EVA Periodic Health Status Examination – Stow S/G2 MRM2 Comm Config Equipment gathering for Orlan-ISS No.5 Ops Combustion Integrated Rack Alignment Guide Install Environmental Health System (EHS) Acoustic Dosimeters – Data Transfer and Stow Orlan-ISS No.5 Elements Deinstallation ExPress Carrier Avionics Configuration Extravehicular Activity (EVA) Tool Configuring MARES battery discharge status control Comm reconfig for nominal ops Extravehicular Activity (EVA) iPad Contingency Procedures preparation OsteoOmics MELFI/MERLIN Transfer Nikon still camera sync with station time Download Pille Dosimeter Readings Extravehicular Activity (EVA) Tool Audit SARCOLAB. MARES files transfer verification and shutdown OsteoOmics Media Relocate Pille Sensor prep for USOS EVA Extravehicular Activity (EVA) Procedure Review SARCOLAB. PEMS and EMG final stowage SARCOLAB. EPM Laptop relocation for files downlink preparation MSPR GCM Component Deactivation [Deferred] OsteoOmics Media Change Recharging Soyuz 733 Samsung PC Battery (if charge level is below 80%) MARES disconnection and stowage Казбек Fit Check Robotic Workstation (RWS) Setup PILOT-T. Preparation for the experiment Health Maintenance System (HMS) Food Frequency Questionnaire (FFQ) or ISS Food Intake Tracker (ISS FIT) SSC DOUG Setup for EVA MARES stowage assistance PILOT-T. Experiment Ops KASKAD. Manual mixing RWS Video Checkout Extravehicular Activity (EVA) Procedure Conference PILOT-Т. Closeout Evening Preparation Work Equipment Lock (E-LK) Preparation LAB BelAir Wireless Access Point (WAP) Verification MARES-EPM Hard Disk removal and stowage Cabin restow after MARES Closure of SM window shutters 6, 8, 9, 12, 13, 14 Completed Task List Items Veg03 Plant Water/Photo Ground Activities All activities were completed unless otherwise noted. EVA procedures conference MSS power up Three-Day Look Ahead: Friday, 05/12: ExPCA EVA #42 Saturday, 05/13: Water dispensing for Electrowetting Drawer, Skinsuit height measurement, EVA camera disassembly/Airlock deconfig/debrief Sunday, 05/14: Crew off duty, Fluid Shifts hardware gather, Ultrasound setup in Russian Segment QUICK ISS Status – Environmental Control Group: Component Status Elektron On Vozdukh Manual [СКВ] 1 – SM Air Conditioner System (“SKV1”) Off [СКВ] 2 – SM Air Conditioner System (“SKV2”) On Carbon Dioxide Removal Assembly (CDRA) Lab Standby Carbon Dioxide Removal Assembly (CDRA) Node 3 Operate Major Constituent Analyzer (MCA) Lab Operate Major Constituent Analyzer (MCA) Node 3 Operate Oxygen Generation Assembly (OGA) Process Urine Processing Assembly (UPA) Process Trace Contaminant Control System (TCCS) Lab Full up Trace Contaminant Control System (TCCS) Node 3 Off