Chemists investigate the biological function of patellamides

Researchers at Heidelberg University have gained new knowledge on the possible biological function of patellamides. In laboratory experiments, they were able to demonstrate that this natural product displays important catalytic activity in combination with copper(II). The team of scientists headed by chemist Prof. Dr Peter Comba developed a special method to determine whether this activity can also be observed in the patellamide-producing organisms. This means that stable copper(II) patellamide complexes could be confirmed in living cells – which would imply that these compounds can act as catalysts. It may even point to a new type of enzyme.