Rodent Research-5 (RR-5) Systemic Therapy of NELL-1 for Osteoporosis: The crew completed injections of the mice in the Microgravity Science Glovebox (MSG) for the RR-5 investigation. Spaceflight has significant and rapid effects on the musculoskeletal system; therefore, it is important to investigate targeted therapies that could ameliorate some of the detrimental effects of spaceflight. The NELL-1 drug being studied in the RR-5 investigation has the potential to slow or reverse bone loss during spaceflight. Multi Omics-Mouse: The crew completed preparation and checkout of hardware and facilities to be used for JAXA’s Multi Omics-Mouse investigation. Rodents for this investigation will arrive on the SpaceX-12 vehicle. The Cell Biology Experiment Facility (CBEF) Back Up Interface was removed and the Mouse Habitat Cage Unit was installed in the CBEF Incubator Unit. Later today the crew till take images of the Cage Unit with the Ghost camera. Compound Specific Analyzer-Combustion Products (CSA-CP) Maintenance: The crew completed this routine maintenance to replace the battery packs in all CSA-CPs and zero calibrate all the units. Today’s Planned Activities All activities were completed unless otherwise noted. SODF Replacement on iPads and Samsung Tablets Preparation of Reports for Roscosmos Web Site and Social Media URAGAN. Observation and Photography ECON-M. Observation and Photography Reminder 1 Vascular Echo Leg Cuffs Ultrasound Scan Hematocrit. Hematocrit Number Hematocrit Hardware Restow Water Recovery and Management Condensate Pumping Init Cell Biology Experiment Facility (CBEF) Back Up Interface Unit Removal Compound Specific Analyzer-Combustion Products (CSA-CP) Extended Maintenance R&R of Nitrogen Pressurization Control Unit (БА СПА) in the FGB Mouse Habitat Unit Interface Unit Installation Water Recovery and Management Condensate Pumping Term Quick-disconnect screw clamps (ЗВБ) maintain Total Organic Carbon Analyzer (TOCA) Calibration Check AMS Hard Drive Change Combustion Integrated Rack Alignment Guide Removal Commercial Generic Bioprocessing Apparatus 6 Removal Environmental Health System (EHS) – Rad Detector Rotate NanoRacks Module-70 Removal from Glacier NanoRacks Module-70 Imagery Cell Biology Experiment Facility (CBEF) Mouse Habitat Cage Unit Installation NanoRacks Module-70 Glacier Insert TangoLab Card Cube Remove Audit of Docking and Internal Transfer System (ССВП) on ISS RS Microbial Tracking-2 Operations Review Dose Tracker Data Entry Subject [Aborted] On MCC Go ISS O2 Repress from the 2nd Section of Progress 435 (DC1) Oxygen Supply System СРПК Rodent Research Node 2 Camcorder Video Setup Rodent Research 5 Injection 2B Rodent Research MELFI Retrieve 4 On MCC Go ISS O2 Repress from the 2nd Section of Progress 435 (DC1) Oxygen Supply System СРПК Rodent Research MELFI Retrieve 8 Rodent Research MELFI Retrieve 5 Rodent Research 5 Injection 2A Unpacking of First Priority and USOS Cargo Items from Progress 436 (SM Aft). IMS Update Total Organic Carbon Analyzer (TOCA) Calibration Check Data Record Total Organic Carbon Analyzer (TOCA) Waste Water Bag (WWB) Changeout Regenerative Environmental Control and Life Support System (RGN) Wastewater Storage Tank Assembly (WSTA) Fill Metal Oxide (METOX) Regeneration Termination Long Duration Sorbent Testbed Status Check. Ghost Camera Setup Cell Biology Experiment Facility (CBEF) Door Open Ghost Camera Real-Time Downlink Checkout Cell Biology Experiment Facility (CBEF) Door Close Ghost Camera Closeout NEEMO/ISS Crew Conference Microbial Tracking-2 Reminder for Saliva Collection Completed Task List Items Declic Data Cable Exchange Ground Activities All activities were completed unless otherwise noted. ROSA Ops Rodent Research Ops Battery Capacity Test for set 3B2 Three-Day Look Ahead: Saturday, 06/24: Crew off duty, housekeeping Sunday, 06/25: Crew off duty Monday, 06/26: Seedling Growth ops, Surface Sampling, HRF ops QUICK ISS Status – Environmental Control Group: Component Status Elektron On Vozdukh Manual [СКВ] 1 – SM Air Conditioner System (“SKV1”) Off [СКВ] 2 – SM Air Conditioner System (“SKV2”) On Carbon Dioxide Removal Assembly (CDRA) Lab Standby Carbon Dioxide Removal Assembly (CDRA) Node 3 Operate Major Constituent Analyzer (MCA) Lab Idle Major Constituent Analyzer (MCA) Node 3 Operate Oxygen Generation Assembly (OGA) Process Urine Processing Assembly (UPA) Process Trace Contaminant Control System (TCCS) Lab Full up Trace Contaminant Control System (TCCS) Node 3 Off