Gata4 alone is able to reduce post-heart attack fibrosis and improve cardiac function in a rat model of heart attack. In rat fibroblasts in the lab, the molecular mechanism involves reduced expression of Snail, the master gene of fibrosis.
Gata4 alone is able to reduce post-heart attack fibrosis and improve cardiac function in a rat model of heart attack. In rat fibroblasts in the lab, the molecular mechanism involves reduced expression of Snail, the master gene of fibrosis.