The HIV-1 capsid protein (CA) interacts with viral factors that support infection and host factors that restrict it. The host protein cyclophilin A (CypA) binds to CA and enhances the action of host restriction factors that block HIV-1 infection.
The HIV-1 capsid protein (CA) interacts with viral factors that support infection and host factors that restrict it. The host protein cyclophilin A (CypA) binds to CA and enhances the action of host restriction factors that block HIV-1 infection.