Researchers from the Epigenetics and Cancer Biology Program of the Bellvitge Biomedical Research Institute (IDIBELL), led by Dr. Àlex Vaquero, have proposed a new regulation mechanism of the NF-κB pathway, which is associated with accelerated cellular aging, based on the analysis of the function of the SirT6 protein. The results of their work, published in Nature Communications, indicate a double mechanism of inhibition of the pathway linked to the action of SirT6 on chromatin.