Researchers of the ICN2 Oxide Nanophysics Group led by ICREA Prof. Gustau Catalan have resolved one of the great unknowns in bone remodelling: how the cells responsible for forming new bone tissue are called into action. Their work reveals the possible role of an electromechanical phenomenon at the nanoscale, flexoelectricity, not only in stimulating the cell response, but in precisely guiding it throughout the fracture repair process.