Genetic analysis uncovers the evolutionary origin of vertebrate limbs

As you picture the first fish to crawl out of primordial waters onto land, it’s easy to imagine how its paired fins eventually evolved into the arms and legs of modern-day vertebrates, including humans. But a new study by researchers from the University of Chicago and the Andalusian Center for Development Biology in Spain shows how these creatures used an even more primitive genetic blueprint to develop their proto-limbs: the single dorsal, or back, fin common to all jawed fish.