Optical Mammography, or OM, which uses harmless red or infrared light, has been developed for use in conjunction with X-rays for diagnosis or monitoring in cases demanding repeated imaging where high amounts of ionizing radiation should be avoided. At the OSA Biophotonics Congress: Biomedical Optics meeting, held 3-6 April in Hollywood, Florida, USA, researchers from Milan, Italy, will report an advance in instrument development that increases the sensitivity of OM by as much as 1000-fold.