Structure of a protein complex related with cell survival revealed

A team from the Spanish National Cancer Research Centre (CNIO) has determined for the first time the high-resolution structure of a complex (R2TP) involved in key processes for cell survival and in diseases such as cancer. This achievement was made with high-resolution cryo-electron microscopy, a technique brought to the CNIO by Óscar Llorca, director of the Structural Biology Programme and lead author on the paper published in Nature Communications.