Engineered Chinese shrub produces high levels of antimalarial compound

Artemisinin is a potent antimalarial compound produced naturally by the Chinese shrub Artemisia annua, commonly known as sweet wormwood. Currently,however, the low amount of artemisinin produced in the leaves of this plant does not meet the global demand. In a study published by April 24 in the journal Molecular Plant, researchers in China report a high-quality draft genome sequence of A. annua and their use of this information along with gene expression data to metabolically engineer plant lines that produce high levels of artemisinin. World Malaria Day is observed on April 25.