Scientists have found a new way of joining groups of atoms together into shape-changing molecules — opening up the possibility of a new area of chemistry and the development of countless new drugs, microelectronics and materials. Discoveries of new ways to make isomers — molecules made of the same atoms connected together differently — were last reported in 1961 and before then in 1914. Proof-of-principle and prototype demonstration of this important finding are expected within 30 months.