The mechanism of DNA binding of the well-studied protein Polycomb, which is vital for cell division and embryogenesis, has finally been deciphered. A remarkable discovery, as it proves that the shape of DNA is at least as important for where the protein binds in the DNA as the DNA sequence. The role of the shape of DNA had not been demonstrated so clearly. Researchers at Radboud University will publish their findings on May 28th in the scientific journal Nature Genetics.