A computer built to mimic the brain’s neural networks produces similar results to that of the best brain-simulation supercomputer software currently used for neural-signaling research. Tested for accuracy, speed and energy efficiency, this custom-built computer named SpiNNaker, has the potential to overcome the speed and power consumption problems of conventional supercomputers, with the aim of advancing our knowledge of neural processing in the brain, including learning and disorders such as epilepsy and Alzheimer’s disease.