Abstract: The High Performance Spaceflight Computing (HPSC) project is dramatically advancing the state of the art for spaceflight computing, providing both increased performance and greater operational flexibility. Initial studies derived an reference architecture for the HPSC Chiplet, and this has evolved as development has progress. NASA and JPL are jointly developing HPSC Middleware to ease the development of future applications for the Chiplet. Several NASA use cases are identified for HPSC, rangi…