Abstract: In our search for life – whether within the earliest part of Earth’s geologic record, on planets within our solar system such Mars, or especially for extrasolar planets – we must infer the presence of life from its impact on the local or global environment. These “biosignatures,” often identified from the known influence of terrestrial organisms on the Earth’s atmosphere and surface, could be misdiagnosed when we apply them to alien worlds. The so-called false positives may occur when another…