Abstract: Exploration Mission 2 (EM-2) will be NASA’s first manned flight on the Space Launch System (SLS) and Orion Spacecraft. The mission has been changed from an SLS Block 1B configuration to Block 1. This change has necessitated a reexamination of the flight profile to determine what changes must be made in order to accommodate the reduced launch vehicle performance on the Block 1. Launch availability and orbital debris risk will be traded to find the best flight profile for both SLS and Orion.