CRISPR/Cas9 improves with better gene knockout method in aneuploid cell lines

CRISPR/Cas9 technology enables convenient and effective genome editing in diploid cell lines based on the isolation and expansion of edited single-cell clones. However, this approach is ineffective for aneuploid cell lines, and a group has now reported an improved method for genome editing based on multiple rounds of modification. The article is published in Tissue Engineering.


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Source: Phys.org