Sigma receptors are proteins found mainly on the surface of endoplasmic reticulum (ER) in certain cells. Sigma-1 and sigma-2 are the two main classes of these receptors. The sigma-1 receptor is involved in neurological disorders and certain types of cancer. To understand better how the receptor is involved in disease and whether drugs developed to target it are working, it is important to be able to accurately trace the sigma-1 receptor. Researchers at Kanazawa University have developed a probe, which can identify and latch onto the sigma-1 receptor.
Click here for original story, Mapping and measuring proteins on the surfaces of endoplasmic reticulum (ER) in cells
Source: Phys.org