The analysis of gene products in cells is an important tool for diagnosing disease and the design of new active substances in biological and medical research. At Helmholtz Zentrum München, a method of targeted RNA sequencing (transcriptome analysis) has now been developed, which precisely detects the smallest amounts of gene transcripts in single cells. The method enables the identification and enrichment of individual selected molecules in a sample in order to investigate their cellular function. This makes it possible to selectively characterize genes in each cell with high precision. Their work has been published in Genome Biology.
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Source: Phys.org