To better understand how tissues and organs develop, fail to function, and regenerate over time, researchers would like to visualize their constituent cells’ repertoires of molecules within 3-D space. Ambitious efforts like the “Human BioMolecular Atlas Program”, the “Human Cell Atlas Project”, and several brain atlas projects are underway to map the presence and abundance of many proteins—the products of gene expression—in organs and tissues of the human body at the scale of single cells. However, existing imaging methods are typically limited in various aspects of their performance, their accessibility to researchers, or both.
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Source: Phys.org