The enzyme transhydrogenase plays a central role in regulating metabolic processes in animals and humans alike. Malfunction can lead to serious disorders. For the first time, structural biologists at the Institute of Science and Technology Austria (IST Austria) have now visualized and analyzed the enzyme’s atomic structure with the support of the institute’s newly installed high-end cryo-electron microscope. The study presented in the journal Nature is relevant for the development of currently unavailable therapeutic options.
Click here for original story, High-end microscopy reveals structure and function of crucial metabolic enzyme
Source: Phys.org