To understand how individual molecules play their roles in biological processes inside the cells they are synthesized in, researchers have developed super-resolution microscopy methods to visualize them at the single-molecule level. However, to investigate their functions, ultimately, they would also like to be able to modify them individually at this high resolution. While the visualization of single molecules has made great strides in recent years, thus far it has remained challenging to directly modify them in a controlled, molecule-to-molecule fashion.
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Source: Phys.org