Human red blood cells (RBCs) are extremely resilient and have the capacity to undergo cellular deformation as they navigate across various micro-vessels and capillaries. Over their 120-day normal lifespan, RBCs must undergo significant cyclic deformation through large elastic stretching and relaxation. Pathological deformations in RBCs are associated with various diseases such as malaria, sickle cell anemia, diabetes, myocardial infarction and various hereditary disorders.
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Source: Phys.org