For all the attention the human microbiome has been getting over the last few years, one aspect of such research rarely makes headlines: the difficulty of observing how it changes over time in response to various stimuli. The most common analysis method is extracting bacteria from fecal samples and then sequencing their genomes, but this approach, while minimally invasive, loses crucial information about where and when bacterial changes occur in the gut, providing scientists with an incomplete picture of the dynamics of the microbiome.
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Source: Phys.org