Tracking the lateral position of single cells and particles plays an important role in evaluating the efficiency of microfluidic cell focusing, separation and sorting. Traditionally, the performance of microfluidic cell separation and sorting is evaluated either by analyzing the input and collected output samples requiring multiple steps of off-chip analysis or the use of expensive equipment (e.g., flow cytometry), or by detecting the lateral positions of cells using an expensive high-speed imaging setup with intricate image processing algorithms or laborious manual analysis. Hence, there is a great need to develop a simple approach for the lateral position measurement of flowing particles.
Click here for original story, Simultaneous measurement of biophysical properties and position of single cells in a microdevice
Source: Phys.org