DNA replication is a tightly regulated process that ensures the precise duplication of the genome during cell proliferation. Replication origins determine where replication starts on the genome and regulate the whole genome replication program. The human genome contains tens of thousands of origins; however, only about 10 percent of them are used in each cell cycle. So how are origins selected?
Click here for original story, Scientists reveal function of histone variant H2A.Z in DNA replication selection
Source: Phys.org