Cryogenic electron microscopy, or cryo-EM, has reached the point where researchers could in principle image individual atoms in a 3-D reconstruction of a molecule—but just because they could see those details doesn’t always mean they do. Now, researchers at the Department of Energy’s SLAC National Accelerator Laboratory and Stanford University have proposed a new way to quantify how accurate such reconstructions are and, in the process, how confident they can be in their molecular interpretations.
Click here for original story, Atom or noise? New method helps cryo-EM researchers tell the difference
Source: Phys.org