A good indicator of dysregulation in live cells is a change in their RNA expression. MicroRNA (miRNA), a special type of RNA, is considered a biomarker for carcinogenic cells. A team of scientists from China has found a way to amplify miRNA in live tumor cells for bioimaging. As they report in the journal Angewandte Chemie, their assay is based on a robust cellular autocatalytic biocircuit triggered by synthetic DNA and nanoparticles.
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Source: Phys.org