Inside our cells, DNA is tightly packed and spooled around proteins called histones. Packaging DNA in this way allows large amounts of genetic material to exist inside the cell in a final form called chromatin. Tiny enzymes modify the histones to make sure the genes that are part of the DNA can be accessed and precisely regulated. The result of this is proper gene expression and the production of proteins important for cell function and human health. When this process goes awry, the result can be diseases such as cancers.
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Source: Phys.org