New technique allows scientists to measure mitochondrial respiration in frozen tissue

Scientists led by Dr. Orian Shirihai, director of the metabolism theme at the David Geffen School of Medicine at UCLA, have developed a method for restoring oxygen-consumption activity to previously frozen mitochondria samples, even years after they have been collected. The process of freezing and thawing mitochondria depresses their oxygen consumption and, until now, has hindered researchers’ ability to accurately carry out large-scale studies examining the crucial role of mitochondria in both health and disease.


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Source: Phys.org