Cells relax their membrane to control protein sorting

The tension in the outer membrane of cells plays an important role in a number of biological processes. A localized drop in tension, for example, makes it easier for the surface bend inward and form invaginations that will become free vesicles inside the cell. These are delimited by a membrane that contains all proteins originally present in the invaginations. A fundamental function of these so-called endosomes is to sort proteins to their cellular destination, e.g., reuse or degradation. Are the functions of endosomes modulated by variations in tension?


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Source: Phys.org