As you drift into unconsciousness before a surgery, general anesthetic drugs flowing through your blood are putting you to sleep by binding mainly to a protein in the brain called the γ-aminobutyric acid type A (GABAA) receptor. Now UT Southwestern scientists have shown exactly how anesthetics attach to the GABAA receptor and alter its three-dimensional structure, and how the brain can tell the difference between anesthetics and the psychoactive drugs known as benzodiazepines—which also bind to the GABAA receptor. The findings were published online today in the journal Nature.
Click here for original story, Study details how general anesthetics and ‘benzos’ act on receptors in the brain
Source: Phys.org