In optical microscopy, high-speed volumetric imaging is limited by either the slow axial scanning rate or aberrations introduced by the z-scanning mechanism. To overcome these limitations, scientists at UT Southwestern have introduced a novel optical design that transforms a lateral-scan motion into a scan in the third dimension. Their microscope realized laser focusing at a rate of 12 kHz and allowed observation of fast dynamics inside cells and the beating heart in Zebrafish embryos.
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Source: Phys.org