Looking at the precise three-dimensional arrangement of atoms within a protein helps us to understand how it can perform its functions. Although electron cryo-microscopy (cryo-EM) has developed rapidly as an important structural biology technique in recent years, X-ray crystallography had been the only technique able to visualize individual atoms. Radu Aricescu’s and Sjors Scheres’ groups at the MRC Laboratory of Molecular Biology, in collaboration with scientists at Thermo Fisher Scientific and elsewhere, have now been able to resolve individual protein atoms for the first time in a three-dimensional cryo-EM image.
Click here for original story, Scientists break resolution records to visualize individual atoms with single-particle cryo-EM
Source: Phys.org