Researchers from UCPH have discovered how a mysterious function of the so called minichromosome maintenance (MCM) proteins protect the human cells against DNA instability, which can cause devastating diseases including cancer. In addition to their known role as molecular motors of genome duplication, MCM proteins in inactive state are now found to control the speed of this process. How cells manage to constrain the speed of DNA replication has puzzled researchers for decades and has even been called a ‘MCM paradox.’
Click here for original story, Researchers solve longstanding ‘protein paradox’ and suggest way to exploit cancer weakness
Source: Phys.org