What does the defense against bacterial infections have in common with hearing or fertilization? Key players in these and many other crucial biological processes belong to a large family of extracellular proteins using a common polymerization engine known as “zona pellucida (ZP) module.” Detailed information on how ZP module proteins look like in their functional polymeric state has so far remained elusive. Now researchers at KI have finally shed light on this long-standing question.
Click here for original story, Cryo-EM meets uromodulin, guardian against urinary tract infections
Source: Phys.org