The binding of a SARS-CoV-2 virus surface protein spike — a projection from the spherical virus particle — to the human cell surface protein ACE2 is the first step to infection that may lead to COVID-19 disease. Researchers computationally assessed how changes to the virus spike makeup can affect binding with ACE2 and compared results to those of the original SARS-CoV virus (SARS).
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Source: ScienceDaily