There are many different events which may lead to excessive and uncontrolled bleeding within the body. This can occur as a result of inflammation and ulcerations, abnormalities in the blood vessels or trauma-related injuries. Individuals with predisposing conditions, such as cardiac patients, are at particular risk of internal bleeding due to the anticoagulants they are often prescribed as a preventive measure. They are also prone to gastrointestinal bleeds, affecting 40% of patients who are on cardiac assistance devices. In addition to the need for an effective treatment for these conditions, there are also indications for controlling the blood flow that contribute to aneurysms and tumor cell vascularization.
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Source: Phys.org