Some of the best-known human pathogens—from the plague bacterium Yersinia pestis to the diarrhea pathogen Salmonella—use a tiny hypodermic needle to inject disease-causing proteins into their host’s cells, thereby manipulating them. This needle is part of the so-called type III secretion system (T3SS), without which most of these pathogens cannot replicate in the body.
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Source: Phys.org